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HMB Study Results Too Good to Be True

The latest finding on HMB supplementation could be more about profit than performance.

Doug Dupont

Written by Doug Dupont Last updated on Nov 22, 2021

You may have seen an article I wrote recently covering the amazing results of a study on HMB and its effects on muscular growth. Recently a different journal, the Journal of the International Society of Sports Nutrition, released another study on the effects of HMB supplementation, but this time on its cardiovascular benefits.

In the previous article, I mentioned some of the researchers had been paid by a supplement company. Couple that with extraordinary results and things seemed fishy, even in an otherwise well-designed study. So let’s take a look at the new research.

Most of the participants in this study performed intervals on a bike three times per week for four weeks. Half of these took 3g per day of free-acid HMB, and the other half took a similar-looking placebo. The rest of the participants did nothing but their normal activities during the four-week period. Before and after the four-week period, each participant was tested on several cardiovascular qualities, including VO2 peak, ventilator threshold, and time to exhaustion on a bike.

First, let’s go over the conclusions. The researchers stated that the group taking HMB significantly increased the cardiovascular fitness variables noted above. As such, they concluded that HMB is great for cardio, too. Combine that with the other recent study on muscle building and it seems that HMB is practically magic. A quick glance at the competing interests shows none whatsoever. Slam dunk, right? Time to head to the vitamin store.

Unfortunately, upon closer examination you will notice the HMB group improved, no doubt, but so did the placebo group. In fact, only ventilatory threshold was better in the HMB group. And don’t get too distracted by the graph showing HMB is better at developing VO2 peak, which claims it’s adjusted for pre-testing values, because it clearly is not. The HMB group started with higher VO2 peak, and the increases are comparable between groups.

It’s odd that two different journals reported amazing or shady results on the same supplement. Truth is, the same supplement company, Metabolic Technologies Inc., provided the supplements and funding for both studies. MTI also employed several of the researchers who took part in the first HMB study I wrote about.

After seeing this, I figured the case was almost closed, but I kept digging. It didn’t sit right that the grad students who worked on the new study seemed to truly have no competing interests. Then I found another article I wrote a while back detailing the stance the Journal of the International Society of Sports Nutrition took on HMB. The conclusion by this illustrious journal was that HMB was great, and its free-acid form might be even better, based on virtually no information.

That stance included contributions by an editor-in-chief of that journal, Jose Antonio, who is also a sports science consultant for a supplement company. Two of the other contributors to that study work at the same university as the researchers in today’s study. And one of them is also employed by – wait for it – MTI, one of the very few companies who provides the free-acid form of HMB.

It’s too bad, because this supplement shows so much promise. Unfortunately, it’s tainted by what appears to be a corporate effort to turn the scientific process into something that no one would call science, just to make a buck.

References:

1. Edward Robinson, et. al., “High-intensity interval training and ß-hydroxy-ß-methylbutyric free acid improves aerobic power and metabolic thresholds,” Journal of the International Society of Sports Nutrition 2014, 11:16

Photo courtesy of Shutterstock.

Doug Dupont

About Doug Dupont

Having grown up at the foot of a forest covered mountain in rural Vermont, Doug was active from a very young age. Hiking, running, and climbing were a part of everyday life in the Green Mountains. This culture of exercise led to dabbling in martial arts as a teen, and also getting work in a local powerlifting focused gym. Doug continued to pursue knowledge and training in exercise, becoming a certified personal trainer while still a teenager. Once in college he began his hand at the business side of fitness, taking a management position at a large local gym. During that time he became a founding member of the UVM Brazilian Jiu Jitsu club, and was the first among their competition team. After only a few months he was assisting in coaching, and ran conditioning program for the club.

Out of college Doug set up his own training center. He grew his list of clientele including several professional MMA athletes, eventually going so far as to corner a world title fight. He has continued ­­­to develop his business into today.

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